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Product: MicroLactin

Company: Swiss Herbal

Size: 120 Capsules

Ingredients: MicroLactin (Milk Protein Concentrate) 500 mg. In a capsule composed of gleatin and purified water.

Dosage: Clinical studies support using a loading dose of 4 capsules twice a day for the first 7 days followed by a maintenance dose of 2 capsules twice daily thereafter. May be taken with or without a meal.

Description: Swiss MicroLactin is a revolutionary new dietary supplement clinically proven to promote healthy joint function. This unique product has been shown in published clinical trials to significantly decrease temporary joint pain and stiffness and significantly improve mobility and range of motion. It is well tolerated and easy to take.

The active ingredients in Swiss MicroLactin are concentrated milk proteins. These proteins are found naturally in cow's milk and are comprised of unique antibodies and other bioactive micronutrients. Using a patented process that isolates and concentrates these natural proteins in sufficient quantities, MicroLactin can be encapsulated.

Swiss MicroLactin works by making the "tight junctions" of the blood vessels even tighter. This in turn significantly reduces the emigration of neutrophils to the site of inflammation (i.e. sore joints). As a result, the cycle of inflammation and pain is broken resulting in better feeling joints, increased flexibility and quicker joint recovery.

Mechanism of Action:
Joint conditions like osteoarthritis are usually associated with inflammation, pain and stiffness in the affected area. Inflammation seen with osteoarthritis is localized to the joint and is multifactorial, but in part neutrophil mediated. Neutrophils are Leukocytes (white blood cells) and form a primary defense against bacterial infection. Like all the cells of the immune system, neutrophils are produced in the bone marrow and circulate in the bloodstream. However, neutrophils move out of blood vessels into infected tissue in order to attack the foreign substance. The escape of neutrophils from the vascular spaces into the joint spaces causes inflammation.

Research has indicated that a low molecular weight component derived from milk protein concentrate has the capability to suppress the emigration of neutrophils from the vascular spaces, into the joint space by up to 75%, thereby decreasing inflammation (ref.1,2). This very unique anti-inflammatory mechanism of action explains the significant improvement in joint pain, joint stiffness and immobility and also accounts for the favourable clinical effects of Swiss MicroLactin.

Clinical Evidence
Through more than 30 years of research and development and 16 clinical trials, Swiss MicroLactin has been proven safe and efficacious. Aside from the improvement in joint health, studies have also demonstrated the significant benefits of Swiss MicroLactin to improve muscle recovery after exercise.

There have been numerous studies done on milk protein concentrate to support its biological activity as a joint care supplement (ref. 1,2,3). To evaluate the effectiveness of Swiss MicroLactin a clinical study was designed and the results were published (ref. 4). Patients were randomized to receive 2000 mg of MicroLactin (twice daily), 500 mg of Glucosamine sulfate (three times daily) or placebo. The Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index was used as a measurement instrument for the assessment of symptoms (ref. 5). WOMAC Osteoarthritis Index is a questionnaire designed to assess the degree of joint pain, joint stiffness and ability to perform daily activities.

There was significant improvement in overall WOMAC scores (pain, stiffness, activities and total WOMAC scores) in the Swiss MicroLactin group, while the glucosamine group had yet to demonstrate noticeable changes in the pain and activity scores. The study also revealed that MicroLactin was more tolerable by individuals as compared to Glucosamine sulfate, due to lower incidences of adverse events.

Swiss MicroLactin is a patented milk protein concentrate clinically proven to reduce the degree of joint pain, joint stiffness and improves the ability to perform the activities of daily living within 4 weeks when taken as directed. Research has shown MicroLactin to be a safe and effective supplement to promote overall joint health. Results should be noticeable with 1-2 weeks of use and improvement will increase with continued daily use. Each capsule of Swiss MicroLactin contains 500 mg of MicroLactin Milk Protein Concentrate.

This product is manufactured under U.S. Patent No. 5,650,175.

Swiss MicroLactin is manufactured in New Zealand under the auspices of the New Zealand Dairy Board. It is produced from pasture fed dairy cows that are antibiotic and hormone-free.

For maximum benefit, Swiss MicroLactin should be taken twice daily - once in the morning and once in the evening. You may take it with or without food.

In clinical studies, no reports of serious adverse events were recorded.

Swiss MicroLactin is 90% lactose free. Only 2 to 5% of the population have an allergy to cow's milk protein. Those individuals should avoid taking MicroLactin. In addition, milk proteins in MicroLactin may interfere with the activity of tetracycline-type antibiotics. Please consult your physician.

References:
1. Ormord D.J., Miller T.E. A low molecular weight component derived from the milk of yper immunized cows suppresses inflammation by inhibiting neutrophil emigration. Agents & Actions 1992;35:1-10

2. Stelwagen K., Ormord D.J. An anti-inflammatory component derived from milk of hyperimmunized cows reduces tight junction permeability in vitro. Inflammation Research 1998;47:384-388

3. Petersen W.E., Campbell B. Use of protective principles in milk and colostrums in prevention of disease in man and animals. Lancet 1955;75:494

4. Zenk J.L., Helmer T.R., Kuskowski M.A. The effects of milk protein concentrate on the symptoms of osteoarthritis in adults: An exploratory, randomized, double blind, placebo controlled trial. Curr Ther Res 2002;63:430-442

5. Bellamy N., Buchanan w.w., Goldsmith C.H., Campbell J., Stitt L.W. Validation study of WOMAC: A health status instrument for measuring clinically important relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of Hip or Knee. J. Rheumatol 1998;15:1833-1840.

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