Celadrin®

One of the newest, most effective, natural anti-inflammatory products is Celadrin, a patented blend of special fatty acids. Celadrin is available in cream, capsules or tablets. Both humans and animals have shown remarkable improvements in terms of reduced pain and swelling, increased range of movement and reduction of inflammatory factors when using Celadrin.

Results of a double-blind, multi-centre, placebo-controlled trial (the most scienti. cally validated type) published in the prestigious Journal of Rheumatology found that Celadrin, when taken orally, improved joint and mobility problems. Sixty-four participants between the ages of 37 and 77 were given Celadrin capsules. They were evaluated at the beginning, at 30 days and at the end of the 68-day study. Compared to those given a placebo, participants taking Celadrin had more flexibility, fewer aches, less pain and were able to walk longer distances than the placebo group.

Celadrin® Joint Care Relief

How Celadrin® Works
Celadrin works similar to, but much more dramatically than, the essential fatty acids EPA and DHA from fish oils. Fatty acids provide many vital, bene. cial effects for the immune and inflammatory responses of the body. Various fatty acids induce changes in cell membranes and the responsiveness of the membrane to certain immune factors. They also play a role in suppressing inflammatory cell functions, decreasing cartilage breakdown (which triggers cell death) and, like NSAIDs, reduce the inflammatory activities of the Cox-2 enzyme.

The esterified (meaning they are stable and do not react with oxygen) fatty acids present in Celadrin have pronounced anti-inflammatory effects, such as the inhibition of inflammation in endothelial cells (thin cells that line the inside of some body cavities) and decreasing the pro-inflammatory effects of other fatty acids like arachidonic acid. The special fatty acids found in Celadrin have also been shown to reduce the production of the negative immune factor IL-6 and to control the immune factors responsible for inflammation. This alone could explain some effects of Celadrin, such as reduction of pain in joints affected by osteoarthritis. These anti-inflammatory functions are very important in preventing further tissue and joint damage while promoting healing. Additionally, the molecules found in Celadrin may play a role in the lubrication of an affected joint. This action, combined with anti-inflammatory effects, explains some of the signi. cant improvements in mobility and function. Such combined effects would appear to be occurring through the application of Celadrin cream in psoriasis. Also, these special fatty acids have been shown to reduce skin inflammation, while providing a sustained moisturizing effect at the site of psoriasis.

Celadrin also works by inhibiting arachidonic acid, one of the main promoters of the inflammatory cascade of immune factors, by inhibiting 5-lipoxygenase – another mediator of inflammation. It may also alter cellular membranes, protecting them from the action of inflammatory cytokines or reducing the secretion of inflammatory cytokines and CRP.